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This adverse effect may negate any benefit on renal function that might be achieved through GLP-1 receptor signaling [91, 92]

However, it's important to note that despite its prospects as an injectable treatment, GHK-Cu's systemic effects are only supported by animal and in vitro studies

10.1136/gutjnl-2020-323617 41 SannaS.van ZuydamN

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