Fatima Cody Stanford, an associate professor of medicine and pediatrics and obesity medicine physician-scientist at the Massachusetts General Hospital and Harvard Medical School, said that as someone who has treated more than 3,000 patients with obesity, she does have strong data supporting the heterogeneity of response to GLP-1R agonists in practice
In certain embodiments, any controlled release otic formulation or composition described herein increases the exposure of a therapeutic agent and increases the Area Under the Curve (AUC) in otic fluids (e.g., endolymph and/or perilymph) by about 30%, about 40%, about 50%, about 60%, about 70%, about 80%, or about 90% compared to a formulation or composition that is not a controlled release otic formulation or composition
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