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Description

Int J Chem Sci

The genetically determined effect of TNF- was inconclusive among patients with CD, as one polymorphism indicated that genetically determined increased TNF- level (rs11465996) and another polymorphism indicated that decreased TNF- level (along with decreased IL-1 and IL-6 levels) (rs3804099) were associated with beneficial response

This ambiguity spans the operational changes in immune cells, alterations in cellular signaling pathways, and the interplay of pro-inflammatory responses between UA-triggered immune cells and tissue-intrinsic cells