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Therefore, asparagine impairs IFN-I release by murine bladder tumor cells, restraining antitumor immunity mediated by recruited CD8 + T cells [222]

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The mitochondrial GTP is probably made by the catalytic function of succinyl-CoA synthetase in the TCA cycle in the matrix or by nucleoside phosphate kinase (NME4) in the mitochondrial intermembrane space [45]