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Clinical studies have demonstrated that topical niacinamide improves the appearance of aging facial skin, including reductions in fine lines, wrinkles, yellowing, red blotchiness, and hyperpigmented spots, while also enhancing barrier function

The most affected areas of the review include section 3.2, Vitamin D levels are often low in persons with PD, where the review discussed the observation that vitamin D levels appear to be lower in persons with PD than in control populations

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