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Strategies to minimise adverse effects include: Ensuring proper injection technique to minimise local reactions Following the recommended dose titration schedule (starting with 0.25 mg weekly) to improve gastrointestinal tolerability Avoiding injection into areas with existing skin conditions or inflammation Rotating injection sites (abdomen, thigh, or upper arm) to prevent localised reactions Maintaining the medication at appropriate storage temperature (28C before first use

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The compounded semaglutide market has grown significantly, and whether compounded formulations carry the same allodynia risk as brand-name products is unknown