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31 Briefly, to 1 g DNA, RNase A (Sigma, St Louis, MO, USA) was added to a final concentration of 0.02 mg ml 1 and incubated at 37 C for 15 min

They measured subjective sleep quality more than objective sleep quality They subjectively estimated tiredness Sleep structure was not fully characterized by polysomnography in all studies Data analysis suggested some observed changes were due to issues with the placebo group What is promising about these findings is that statistically significant effects were found in such small sample sizes

This is a major reason why it is viewed as a safer alternative to full growth hormone

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