Also known as PNB-0408 , Dihexa binds strongly to hepatocyte growth factor (HGF) and interacts with the c-Met receptor
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For example, PDCOs identified differential sensitivity to TAS-102 in metastatic CRC, linking efficacy to thymidine kinase 1 (TK1) expressiona potential predictive biomarker
It is more dangerous with higher doses or prolonged usage
