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Bioavailability refers to the amount of a substance that actually enters your bloodstream and becomes available for your body to use

Serum urate levels in women remain relatively stable overall until menopause, at which time serum urate rises in association with loss of the natural uricosuric effect of estrogen (i.e., loss of the promotion by estrogen of renal excretion of uric acid, which is likely mediated in large part by sex hormone effects on one or more major urate transporters)

10What Safety Aspects Are Known from Research

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