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Patients were randomized 1:1 to receive subcutaneous semaglutide 2.4 mg once weekly or placebo as an adjunct to standard-of-care therapy for CVD, such as cholesterol-modifying medications, antiplatelet therapies and antihypertensive agents

These took significant R&D $ and naturally will see price hikes. Patients have been able to access cheaper forms of insulin for years , but those come with lower half-life and sharper "peaks" that trigger unwanted side effects

One small study showed that patients who took semaglutide within the previous 30 days had approximately 5 times greater risk for the presence of residual gastric contents at the time of the procedure than those who had not taken semaglutide, despite following fasting instructions