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doi: 10.1038/s41598-025-04888-3

The authors of this study pointed out that there appears to have been a slowing of weight regain towards the end of the study, implying a weight loss plateau below the initial pre-treatment weight

Start your intake How Semaglutide Works in Your Body for Weight Loss Semaglutide activates GLP-1 receptors in your hypothalamus, the brain region that regulates hunger and satiety signals

One-way ANOVA showed significant differences between the groups in terms of age ( p = 0.001), hence age was included as a covariate in between group comparisons of metabolite concentrations