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Persistent hunger throughout the day, no change in food noise or cravings, and no weight loss after 4 or more weeks on a stable dose all suggest the dose is too low or absorption is insufficient

Vilsbll T, Krarup T, Sonne J, Madsbad S, Vlund A, Juul AG et al

A month's worth of weekly injections of semaglutide and tirzepatide in the United States in 2024 cost upwards of US $1,000 which puts it out of the reach of many (Blackman)