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However, the reduced blood flow and resulting ischaemia may also act as a stressor itself

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Biomed Pharmacother 57(34):145155 Townsend DM, Manevich Y, He L, Xiong Y, Bowers RR Jr, Hutchens S, Tew KD (2009) Nitrosative stress-induced S -glutathionylation of protein disulfide isomerase leads to activation of the unfolded protein response

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