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Watch for warning signs: Swelling of the tongue, face, lips, or throat Rapid heartbeat, dizziness, or fainting Difficulty swallowing or breathing Severe or widespread rash/hives Call 911 or seek emergency care immediately

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The RNA yield was determined using a NanoDrop 2000 Spectrophotometer (Thermo Scientific, Waltham, USA), and the integrity was evaluated using agarose gel electrophoresis with ethidium bromide stain