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Under normal conditions, A1AT expression is regulated by promoters, while during inflammatory responses, it is stimulated by various factors

(PubMed) Bougma K, Aboud FE, Harding KB, Marquis GS

Symptoms of low testosterone in males can include: Decrease in sex drive Difficulty getting or maintaining an erection Decrease in muscle mass Bone weakness Breast tissue development Hair loss Difficulty sleeping Difficulty with memory and concentration Decrease in testicle size Decrease in semen production that can lead to fertility problems Symptoms of high testosterone in males can include: Elevated blood pressure Heart or liver problems Headaches Aggressive behavior Excessive body hair growth Acne Prostate enlargement Decrease in sperm production Insomnia Symptoms of low testosterone in females are not well characterized

& FitzGerald, G