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Accumulated evidences have shown that urolithin A exhibits multiple protective effects inducing mitophagy in heart (Huang et al., 2022c), muscle (Luan et al., 2021) and brain (Jayatunga et al., 2021)

It is conceivable that in ASD, neuronal hyperexcitationconsistent with the excitatory-inhibitory imbalance hypothesistriggers compensatory excessive inhibition in specific brain regions, which may be reflected by elevated GABA concentrations

Metabolic regulation of somatic stem cells in vivo