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Combination therapy is mechanistically plausible but remains insufficiently supported by dedicated randomized evidence in HF populations

Microsphere production Microspheres were produced by a modified reverse emulsion polymerization method [13]

Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71