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Tumor invasion into all layers of the cerebral cortex was revealed (Figure 3b), while the white matter of the brain remained intact

Importantly, this concept does not imply overt NAD depletion

Wu H, Zhao G, Liu S, Zhang Q, Wang P, Cao Y, Wu L (2022a) Supplementation with selenium attenuates autism-like behaviors and improves oxidative stress, inflammation and related gene expression in an autism disease model