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Doses used were well tolerated by patients, while only mild adverse effects were reported (heartburn, nausea, flatulence) [60]

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Neuroimaging studies have found that patients with hyperthyroidism had reduced grey matter volume in portions of the occipital lobe (lateral occipital sulcus and fusiform gyrus) in the left hemisphere, the frontal and parietal lobes (insula, paracentral, precuneus, superior frontal cingulate, superior parietal and postcentral) in the right hemisphere