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Macimorelin Test Macimorelin (formerly AEZS-130) is a synthetic ghrelin receptor agonist (also known as a GH secretagogue) with GH-secreting properties similar to those of endogenous ghrelin, but with improved stability and better oral bioavailability than other GH secretagogues such as GHRP-6

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A reduction in her autism severity from ASD level 2 (mild to moderate) to level 1

In addition, given the inherent day-to-day variability in function in the frail target population as well as the presence of a host of concomitant conditions, the appropriate patient population to be studied remains to be defined, and demonstration of clinically meaningful efficacy may be difficult