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AOD-9604 achieves selective fat metabolism by targeting beta-3 adrenergic receptors in adipose tissue without binding to growth hormone receptors that mediate IGF-1 production, glucose metabolism, and tissue growth

Found in green tea, it has antioxidant, anti-inflammatory and neuroprotective effects (Plascencia-Villa and Perry, 2021)

Repeat domains of melanosome matrix protein Pmel17 orthologs form amyloid fibrils at the acidic melanosomal pH

Research in animal models has shown significant reductions in body weight and adipose tissue, with studies reporting up to 50% less weight gain in obese Zucker rats after 19 days of administration