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Medications : Diuretics (often used for hypertension or heart failure) and low-dose aspirin can impair uric acid excretion
A 2025 narrative review that searched six databases through March of that year found robust regenerative signals in preclinical work but only three published human clinical trials of BPC-157 and concluded that the compound should still be considered investigational, noting the anti-doping and compounding restrictions that regulators had applied over the lack of human safety data
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Dosages used in commercial products are often substantially lower than those studied in clinical research
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