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Nonetheless, the underlying reasons for the inconsistencies in the reported associations between T2DM and levels of plasma DPP-4 activity (lower, unaltered, higher) have not been adequately explained, although one study did suggest that it might be related to the populations studied, with changes only becoming evident once moderate or severe hyperglycaemia becomes established (68)

Both act on the same family of receptors, the melanocortin receptors

Review articles like this one synthesise findings from many individual studies to build a complete picture