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Glutamate is a precursor of GSH while GSH acts as a neuronal reservoir for glutamate synthesis [27]

The IL4R-targeted (KLAKLAK)2 peptide acted on IL-4R-high and M2-polarized TAMs as well as tumor cells and reduced the proportion of M2-type TAMs in the tumor microenvironment 54

According to in-vitro analysis, Resveratrol and temozolomide together have been found powerful cytotoxic representatives towards melanoma cells and primarily observed that it results in cell death when it participated in sensitizing melanoma cells to IL-2 immunotherapy & it appears that resveratrol functions effectively in collaboration with other treatment approaches [310]

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