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After accounting for injected volume-equivalents, plasma concentrations were generally higher across metabolites, with GSSG as a notable exception (Figure 6C)

2) Taking the medication incorrectly (not on an empty stomach or not waiting the full 30 minutes before eating) can reduce effectiveness

Key Takeaway: Unopened GLP-1 medications are typically stable in the refrigerator until their printed expiration or beyond-use date, but they must never be allowed to freeze