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AT 2 R activation is important in blunting the negative effects of AT 1 R, such as neuroinflammation and oxidative stress ( 1 receptors predominate in adult tissues and AT 2 receptors predominated in the developing brain ( 2.2 Non-classical pathway: ACE2/Ang-(17)/MasR The non-classical axis is neuroprotective and composes angiotensin-converting enzyme 2/angiotensin-(17)/Mas receptor axis (ACE2/Ang-(17)/MasR)

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Ruder, S

This helps ensure a smooth and even dissolution process