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As treatment continues and the dose is gradually increased, weight loss typically becomes more noticeable over the following weeks

doi: 10.1016/j.chom.2015.10.007 61 BronPAKleerebezemMBrummerRJCaniPDMercenierAMacDonaldTTet al

Despite the fact that the relationship between glucagon and body weight is well established, some research found no changes in food intake following glucagon administration, which suggests that appetite-independent mechanisms may play a role in the glucagon-mediated regulation of body weight [14]