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I never find a clear physical explanation, and I feel that leaves us with an interesting question as to whether Mpemba-like effects exist in a meaningful way. Bechhoefers trials appear to offer some insight into how the Mpemba effect could arise in systems with metastable states, but whether it is the only mechanism or how any particular substance undergoes such out-of-equilibrium heating or cooling is unknown

X-linked G6PD deficiency protects hemizygous males but not heterozygous females against severe malaria

Cant do hot oatmeal but cold protein shake works