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GSEA analysis revealed a significant enrichment of a NRF2 stress-response signature 31

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Second, although SGLT2i monotherapy has been linked to improvements in fatty liver index and lower risk of MALO in MASLD patients, 12,15,28,29,30 , our findings suggest that adding GLP-1RA to SGLT2i provided additional hepatic benefits, reducing the risk of MALO by 39%

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1 2 "Glucagon-like peptide-1: modulator of -cell dysfunction and death"

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