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When we don't get enough iron, we may experience: Reduced capacity to exercise and skeletal muscle atrophy, even before iron deficiency anemia (IDA) develops Over time, IDA, resulting in abnormal red blood cell formation and symptoms such as fatigue, weakness, difficulty concentrating, impaired cognitive and immune function, and poor body temperature regulation IDA has also been linked to impaired glucose metabolism---potentially due to poor conversion of proinsulin to active insulin in the body

For both, the temptation in midlife is to add more products

In the US, an estimated 42 percent of the population are deficient in vitamin D

10.1016/j.bmcl.2008.10.044 Bioorg