Methods Enzymol 2018, 599, 101137
Both HRS-9531 and MET-097 I think have a chance to help break the duopoly into smaller pieces, but itll still take until probably 2027 at the absolute earliest to see this happen and even then itll be a drug not featured during this conference
Paiva I, Seguin J, Grgurina I, Singh AK, Cosquer B, Plassard D, Tzeplaeff L, Le Gras S, Cotellessa L, Decraene C, Gambi J, Alcala-Vida R, Eswaramoorthy M, Bue L, Cassel J-C, Giacobini P, Blum D, Merienne K, Kundu TK, Boutillier A-L (2024) Dysregulated expression of cholesterol biosynthetic genes in Alzheimers disease alters epigenomic signatures of hippocampal neurons
While that initial boost is great, the real goal is to maintain your B12 levels over time so you can enjoy sustained energy and focus without the ups and downs