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Second, evaluating L-carnitine as a background therapy in combination with novel anti-fibrotic agents (e.g., GLP-1/GIP dual receptor agonists, FGF21 analogs) to assess its role in consolidating therapeutic efficacy and reducing relapse risk after drug discontinuation

all were aged 20 years and had no known comorbidities or hand arthralgia

Detailed molecular studies revealed that compound 18 notably inhibited MAPK phosphorylation and the subsequent activation of activator protein 1 (AP-1)