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In another 4-week study including 40 individuals with hypertension found that daily ingestion of 10 g dried broccoli sprouts did not improve endothelial function ( p = 0.05), a trend towards a 10% decrease in diastolic blood pressure was reported in pregnant women with preeclampsia during a recent dose escalation study of activated broccoli extract (equivalent to 32 or 64 mg sulforaphane), regardless of sulforaphane dose ( Dyslipidemia Most of the research investigating the effects of glucosinolate consumption on lipids has been undertaken in animal models

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Senolytic agents include natural compounds such as quercetin 13 or fisetin 14 , -galactosidase-activated nanoparticles and prodrugs 15,16,17 or compounds that target different vulnerabilities of senescent cells, such as HSP90 inhibitors 18 , cardiac glycosides 19,20 or NMT inhibitors 21