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Notably, the hepsin / mice exhibited a more pronounced increase in ROS levels after thioacetamide treatment compared with wild-type mice, which aligned with our hypothesis that hepsin / mice experience heightened ROS stress in the early stages of APAP exposure due to their elevated expression of GJ proteins (Fig

These compounds exhibit significant pharmacological effects in the treatment of thyroid diseases and DM ( Scrophulariae Radix and their mechanisms of action are summarized in Table 1

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Results showed that glutathione supplementation was again associated with suppression in lactate levels, while fatigue measures were also significantly decreased, compared to the placebo group