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RNA transcription and subsequent protein synthesis are less affected by folate deficiency, as the mRNA can be recycled and used again (as opposed to DNA synthesis, where a new genomic copy must be created)

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Evidence shows that certain 5-HT2A agonists with psychedelic properties, such as (R)-DOI (in primary rat aortic smooth muscle cells stimulated with TNF-), can inhibit NF-B nuclear translocation and suppress TNF--induced inflammatory gene expression in vitro, including ICAM-1, VCAM-1, and IL-6