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Iron metabolism in the pathogenesis of iron-induced kidney injury

Ferroptosis inhibition protects vascular endothelial cells and maintains integrity of the blood-spinal cord barrier after spinal cord injury

It can also reduce the accumulation of lactic acid in muscles

To expand on these studies, the effects of RG7697/NNC0090-2746 on glycemic control, body weight, and other metabolic measurements were evaluated in a 12-week double-blind and placebo-controlled phase 2a clinical trial of 108 subjects with T2D inadequately controlled with metformin [83]