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You may consider clinical assessment if: Pigmentation is long-standing or resistant to topical care Melasma remains persistent despite conservative management Post-inflammatory hyperpigmentation does not gradually fade Sun damage is extensive Treatment recommendations should always be individualised after medical evaluation

Gilenya ), a sphingosine analog approved by the U.S

Purity: 98.88% CAS No.: 27025-41-8 Formula: C 20 H 32 N 6 O 12 S 2 Molecular Weight:612.63 Storage: Sealed storage, away from moisture

This project has received funding from the European Unions Horizon 2020 research and innovation programme (grant nos