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450 Analyses of postmortem brain tissues showed an increase in the transcription of numerous glutamate-related genes in the prefrontal cortex in depressed women but not in depressed men

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Furthermore, the changes of plasma antioxidants (GR and GPX) levels showed an opposite pattern of release compared to liver enzymes during this acute phase of dengue infection, where the peak reduction of both antioxidants enzyme levels were observed on the day five of admission suggesting that elevation of AST and ALT could be associated with the oxidative stress induced by the dengue virus [5]