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Glutathione exists in two forms as free glutathione: the reduced thiol form, which is abbreviated GSH the oxidized disulfide form, which is abbreviated GSSG A thiol is a sulfur compound that contains a sulfhydryl group (-SH), which is a sulfur atom attached to a hydrogen atom

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As a direct antioxidant, GSH quenches reactive oxygen species (ROS), reactive nitrogen species (RNS), and lipid peroxyl radicals, and regenerates oxidised vitamin E and vitamin C back to their active reduced forms placing GSH at the hub of the broader cellular antioxidant network