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If urine albumin excretion remains abnormal, further therapy (based on individual preferences) with an SGLT2i, nsMRA, and/or GLP1-RA with proven kidney protection will help slow CKD progression and reduce cardiovascular outcomes (Figure 6)

Everyones response is different, so an experienced physician should manage titration and help address any side effects, he said

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If initiating with insulin or a sulfonylurea, proactive dose reductions of those agents may be considered to avoid hypoglycemia