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Tirzepatide has been associated with modest increases in resting heart rate (mean increase of 24 bpm in clinical trials), though the mechanism is unclear

Vitamin B12 (also known as cobalamin) is a water-soluble vitamin that plays a key role in: Normal red blood cell formation Normal energy-yielding metabolism Function of the nervous system Reduction of tiredness and fatigue DNA synthesis Normal psychological function In the UK, these are recognised health claims for vitamin B12 under authorised nutrition and health regulations

Honaker 2008, Hauge 2011 ): avoidance of caffeine, nicotine, red wine, and other migraine triggers stress reduction (see the Stress Management protocol) improving sleep hygiene (see the Insomnia protocol) massage therapy chiropractic manipulation acupuncture getting sufficient exercise and frequent stretching 8 Dietary Interventions A significant association between dietary intake and migraine incidence exists