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FIGURE 3 4 Robust synergistic therapy against cancer 4.1 Sensitized chemotherapy As a chemotherapeutic agent, platinum is one of the most widely used metal-based anticancer components (Makovec, 2019)

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Similarly, the decrease in 3-methyl-2-oxovaleric acid, linked to BCAA metabolism, further supports this and indicates altered amino acid metabolism during epileptic activity 32

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