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Among the SHANK isoforms, the SHANK3 gene is most closely associated with ASD and related neurodevelopmental conditions such as Phelan-McDermid syndrome

By activating the parasympathetic nervous system and assisting patients in recognizing the relationship between stress and dietary habitssuch as through the Mindful Eating Questionnaire (MEQ) and handwritten dietary journalsit helps reduce stress responses and enhance digestive function, thereby promoting more favorable conditions for nutrient absorption

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