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Similarly, ERK (extracellular signal-regulated kinase) and its involvement in melanin synthesis via the ERK/CREB (cAMP response element binding protein) pathway demonstrate how kinases contribute not only to antioxidant defense but also to pigmentation regulation by upregulating MITF and TRP1 69,71

To view a copy of this license, visit About this article Cite this article Begas, P., Liedgens, L., Moseler, A

Upon degranulation, they release histamine, stimulating the nerve to release substance P and glutamate from the nerve terminals

Clearance of p16Ink4a-positive senescent cells delays aging-associated disorders