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This GLP-1R plus strategy, combining GLP-1 RAs with other hormone-based medications that target different pathways, such as amylin or GIP, may result in additive or synergistic effects that enhance weight loss and improve metabolic outcomes

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The GLP-1 activity counterbalances the blood sugar raising effect of glucagon, so the net result is more fat burned without blood sugar problems

However, several studies have been conducted to investigate the association between the consumption of food supplements and drugs containing ephedra compounds and the onset of adverse events [74]