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In searching Reddit communities dedicated to GLP-1 drugs, I found lots of normal people whose experience backed up that research: They had long tried to lose weight but could never quite meet their goals until they went on a GLP-1 drug

Quick Ranking Table Rank Compound Primary pathway Testosterone relevance 1 hCG LH receptor mimic at Leydig cells Strongest direct clinical testosterone-axis relevance 2 Gonadorelin GnRH signaling to pituitary LH/FSH Strong upstream axis relevance when delivered correctly 3 Kisspeptin-10 Kisspeptin receptor / GnRH activation Strong research signal, less practical clinical availability 4 Sermorelin GHRH receptor / GH release Indirect male-hormone-adjacent research 5 CJC-1295 + Ipamorelin GHRH plus GHS-R1a signaling Indirect recovery and GH-axis research 6 PT-141 Melanocortin receptor pathway Sexual-function relevance, not testosterone production 7 Tesamorelin GHRH analog / GH release Useful comparator, weak direct testosterone relevance 1

Decreased levels of total carnitine, free carnitine, and ACs were found in MS and NMO patients