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Animal studies used doses up to 1.1 mg per kilogram of body weight with no adverse effects observed

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However, results are dose-dependent and more effective when combined with a calorie-controlled diet or exercise program Could Help Prevent Fat Storage (Reduced Lipogenesis) Some animal studies suggest AOD9604 may limit the formation of new fat cells, known as lipogenesis (preclinical evidence)

J Mol Model 27:18 Bi L, Yu Z, Wu J, Yu K, Hong G, Lu Z, Gao S (2015) Honokiol inhibits constitutive and inducible STAT3 signaling via PU.1-induced SHP1 expression in acute myeloid leukemia cells