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Weeks 13+: 10-12 mg per week (maintenance) The highest clinical doses

Fine lines and wrinkles (particularly around the eyes and mouth) begin to soften, skin tone appears more even, and the healing of blemishes accelerates

Similar to the time course of neuronal activity in the cerebellar nuclei, temporally specific periodic signals predicting event timing have also been reported in the beta-band coherence of neuromagnetic activity between the cerebellum and the cerebral cortex when listening to an auditory beat [353], suggesting that such signals may provide a basis for the perception of rhythms