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Written informed consent to participate in this study was provided by the participants' legal guardian/next of kin

Insulin syringes come in U40 and U100 formats, which correspond to the insulin content of 40 units per 1 ml and 100 units per 1 ml, respectively

Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly

Patient preferences for the type of delivery (oral vs injectable), regularity of dosage (daily vs weekly) and additional limitations (e.g., taking on an empty stomach and drug interactions) are important to understand in order to design a drug that appeals to the majority of patients and trumps competitor drugs