efficacy of tirzepatide for the treatment adults with type 2 diabetes: An endocrine perspective EFFICACY OF TIRZEPATIDE IN TREATING

Retatrutides glucagon receptor activation increases energy expenditure by promoting thermogenesis and fat oxidation

Side effects from semaglutide, particularly nausea, are typically most prominent in the 24 to 72 hours following injection, especially during dose escalation

Metabolic endpoints (e.g., weight change, HOMA-IR, HbA1c) are most often supported by RCTs and therefore show relatively consistent and reproducible effects

8 Conclusion Tirzepatide, an innovative treatment for type 2 diabetes, has demonstrated significant effects on glycemic control and weight management through the dual activation of GLP-1 and GIP receptors